Blood & Laboratory Values

Vitamin B6 – Function & Diseases

Vitamin B6

Vitamin B6 is called pyridoxine and is water soluble. Vitamin B6, with its components pyridoxol, pyridoxal and pyridoxamine, as a starting substance in the metabolism, takes on its tasks, especially for the formation of coenzymes.

Mode of action of vitamin B6

Coenzymes are important for all processes in protein metabolism. The body can form pyridoxal phosphate, also known as PLP, and pyridoxamine phosphate, also known as PMP, from vitamin B6. Both coenzymes are significantly involved in the formation of various enzymes.

Enzymes act like catalysts and are involved in many biochemical reactions in the body. Both PMP and PLP play a role in at least 100 metabolic processes in the body. If the body wants to build up protein building blocks, it needs PLP above all.

Protein building blocks consist of amino acids on which the PLP has a particularly strong effect. Dopamine and the messenger substance histamine, which is involved in allergic processes , as well as serotonin as a neurotransmitter are influenced by PLP. The entire fat metabolism and the immune system as well as the hormonal balance are also controlled by vitamin B6.


Since vitamin B6 is significantly involved in the immune system and its ability to function, it plays an essential role in health. If the immune system is weak, all other functions gradually suffer and the person becomes ill.

The significant influence of vitamin B6 on the entire nervous system also plays a significant role in maintaining health. Hormonal processes that are not sufficiently supplied with vitamin B6 and a weakened immune system affect all other physical processes that make a body efficient.

Since vitamin B6 plays such a central role in amino acid metabolism, vitamin B6 is also important for preventing diseases. Vitamin B6 also has the same importance in the therapy of various diseases. Only folic acid and vitamin B12 are just as important for the body and its health.

Many problems such as premenstrual symptoms or carpal tunnel syndrome and depression are positively influenced by vitamin B6.

For athletes, vitamin B6 also plays an important role for these reasons. A healthy and balanced diet provides enough vitamin B6. If you do a lot of sport, you should make sure that you take enough vitamin B6. Because athletic performance depends on vitamin B6 in many physical processes.

Occurrence in food

With a balanced diet, the need for vitamin B6 can easily be met, as it is contained in many different foods. Meat eaters in particular meet their vitamin B6 requirements quite well. Liver and meat contain a lot of this important vitamin, which is involved in various metabolic processes.

In general, all animal foods are strong sources of vitamin B6. Offal and fatty fish such as sardines or mackerel provide plenty of vitamin B6. In addition to meat, it is also found in potatoes and cereals, in vegetables and fruit.

Vitamin B6, on the other hand, is not contained in sugar, oils or fats. Milk that has been sterilized has also lost its vitamin B6 content. The vitamin B6 in meat is also lost up to 40 percent during cooking and roasting. Food that is deep-frozen sometimes only contains 50 percent of the essential vitamin B6.

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Hello! I am Lisa Newlon, and I am a medical writer and researcher with over 10 years of experience in the healthcare industry. I have a Master’s degree in Medicine, and my deep understanding of medical terminology, practices, and procedures has made me a trusted source of information in the medical world.